Everything You Need to Know About Panadol Sinus: Ingredients, Dosage, and Warnings

Last updated:21/10/2025

Many people suffer from facial pressure, headaches, or nasal congestion caused by sinus inflammation. One of the most commonly used medications to relieve these symptoms is Panadol Sinus, which provides fast and effective relief when used correctly.

In this article from Magrabi Hospitals, you’ll learn about Panadol Sinus ingredients, the recommended dosage, important warnings before use, and the differences between its types, including the green Panadol Cold & Flu Night Time, as well as guidance for pregnant women, children, and people with high blood pressure.

 

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What Is Panadol Sinus and How Does It Work?

Panadol Sinus is a medication designed to relieve sinus pressure, nasal congestion, and pain associated with colds or allergies.
It combines Paracetamol, a pain reliever and fever reducer, with a nasal decongestant (Phenylephrine) that helps open blocked nasal passages and improve airflow.

The formula targets sinus pressure behind the eyes, cheeks, and forehead, providing noticeable comfort and better breathing during both the day and night.

Ingredients of Panadol Sinus

Panadol Sinus tablets contain two active ingredients:

• Paracetamol (500 mg): Relieves headache, sinus pain, and fever.
• Phenylephrine Hydrochloride (5 mg): Acts as a nasal decongestant by constricting blood vessels inside the nose and reducing swelling.

This combination helps relieve the discomfort caused by sinus inflammation, making breathing easier and reducing sinus pressure.
The product is also marketed under the name Panadol Sinus Relief in some countries.

According to the Saudi Food & Drug Authority (SFDA), always use registered medications that meet safety and quality standards.

Recommended Dosage and How to Use It

• Adults: Take two tablets every 4–6 hours as needed.
• Do not exceed 8 tablets in 24 hours.
• Not recommended for children under 12 years without medical supervision.
• Do not use for more than 7 consecutive days unless advised by a doctor.

The Saudi Ministry of Health advises avoiding multiple medicines containing Paracetamol simultaneously, as this can cause liver damage.

Warnings Before Using Panadol Sinus

Before taking Panadol Sinus, consider the following precautions:

• Do not use if you are allergic to any of its ingredients.
• Consult your doctor if you have high blood pressure, heart disease, or thyroid disorders.
• Avoid taking other medicines containing decongestants or Paracetamol at the same time.
• Panadol Sinus may cause drowsiness in some people—avoid driving or operating heavy machinery after taking it.

While medications like Panadol Sinus can relieve symptoms temporarily, persistent sinus issues may require specialized medical evaluation.

 

Visit our ENT Services Page to learn how Magrabi Hospitals diagnose and treat sinus and nasal conditions effectively.

 

Panadol Sinus for Hypertensive Patients: Is It Safe?

People with high blood pressure should use Panadol Sinus with caution.

Because it contains Phenylephrine, it can temporarily increase blood pressure in sensitive individuals.
If you have hypertension, your doctor may recommend safer alternatives such as plain Paracetamol or saline nasal sprays.

Always consult a healthcare professional before using decongestants if you have chronic cardiovascular conditions.

Panadol Sinus for Pregnant Women and Infants

Panadol Sinus is not recommended during pregnancy unless approved by a physician, as some decongestant ingredients may not be safe for the fetus.
It should not be used for infants or young children—instead, use paediatric formulations specifically designed for their age group.

Pregnant and breastfeeding women should always consult their doctor before taking any medication containing decongestants.

Panadol Cold & Flu Night Time (The Green One)

The product commonly known as the green Panadol Sinus is actually Panadol Cold & Flu Night Time.
It is designed to relieve cold and flu symptoms that may occur alongside sinus congestion, especially at night.

It contains Paracetamol to reduce pain and fever, and an antihistamine (Chlorphenamine Maleate) that reduces nasal discharge, helps clear congestion, and promotes restful sleep.

While it can ease sinus-related symptoms, it is not a direct treatment for sinus inflammation.
It’s best taken in the evening, as it may cause drowsiness, helping patients rest while recovering from colds.

According to the Saudi Food & Drug Authority, users should strictly follow dosage instructions and avoid prolonged use to prevent side effects.

The Difference Between Panadol Sinus and the Green Panadol (Cold & Flu Night Time)

Although both are Panadol products, they serve different purposes:

Feature	Panadol Sinus (Original)	Panadol Cold & Flu Night Time (Green)
Main Use	Relieves sinus pressure, nasal congestion, and headache	Relieves cold and flu symptoms at night
Key Ingredients	Paracetamol + Phenylephrine	Paracetamol + Chlorphenamine (antihistamine)
When to Use	Daytime	Nighttime (causes drowsiness)
Effect on Sleep	Non-drowsy formula	Promotes better sleep

In short, Panadol Sinus is ideal for daytime sinus relief, while the green Panadol Cold & Flu Night Time is best for nighttime comfort and sleep.
Doctors at Magrabi Hospitals advise not to combine both without medical guidance to avoid exceeding the safe Paracetamol dose.

FAQs About Panadol Sinus

What is the best Panadol for sinus infection?

The best option is Panadol Sinus, as it combines Paracetamol and a decongestant to relieve headache and sinus pressure effectively.

Can Panadol relieve sinus inflammation?

It can ease pain, pressure, and congestion, but it doesn’t cure the underlying inflammation.
Consult your doctor if symptoms persist beyond a few days.

What is the best medicine for cold and sinus?

Panadol Sinus works well for mild sinus congestion due to colds, but if bacterial infection is suspected, your doctor may prescribe antibiotics.

Doctors’ Tips Before Taking Panadol Sinus

• Never use the medicine for longer than the recommended duration.
• Consult a doctor if you have hypertension, heart disease, or thyroid problems.
• Avoid using other products that contain Paracetamol or Phenylephrine simultaneously.
• Drink plenty of water and rest to support faster recovery.

Possible Alternatives to Panadol Sinus

• Panadol Science or other brands containing similar ingredients.
• Saline nasal sprays to clear nasal passages.
• Steam inhalation and humidifiers to relieve congestion naturally.

Conclusion

Panadol Sinus remains one of the most effective over-the-counter options for relieving sinus pressure, headaches, and congestion when used correctly.
However, safe use always begins with medical advice, especially for patients with hypertension, pregnant women, or children.

 

Breathe better, live better — schedule your ENT consultation today at Magrabi Hospitals for a precise diagnosis and the best sinus care options available.
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References

• Saudi Ministry of Health (MOH)
• Saudi Food & Drug Authority (SFDA)
• Mayo Clinic – Sinusitis Treatment Guidelines
• NHS UK – Sinusitis Overview
   

 

 Edited and medically reviewed by:
Dr. Mohammed Kamel, ENT Specialist at Magrabi Hospitals.

 

Medical Disclaimer

This article is for educational purposes only and should not be considered a substitute for medical advice.
Always consult your doctor before taking any antibiotics or medications approved by the Saudi Food and Drug Authority (SFDA).